Valine dehydrogenase (NAD+)
| Valine dehydrogenase (NAD+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.4.1.23 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Valine dehydrogenase (NAD+) (EC 1.4.1.23) is an enzyme with systematic name L-valine:NAD+ oxidoreductase (deaminating).[1][2] This enzyme catalyses the following chemical reaction
- L-valine + H2O + NAD+ 3-methyl-2-oxobutanoate + NH3 + NADH + H+
The enzyme from Streptomyces spp. has no activity with NADP+.
See also
References
- ↑ Vancurová, I.; Vancura, A.; Volc, J.; Neuzil, J.; Flieger, M.; Basarová, G.; Behal, V. (1988). "Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens". J. Bacteriol. 170 (11): 5192–5196. PMC 211589
. PMID 3182727. - ↑ Navarrete, R.M.; Vara, J.A.; Hutchinson, C.R. (1990). "Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2)". J. Gen. Microbiol. 136 (2): 273–281. doi:10.1099/00221287-136-2-273. PMID 2324704.
External links
- Valine dehydrogenase (NAD ) at the US National Library of Medicine Medical Subject Headings (MeSH)
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